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11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

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Origin: China

Cas No: 641-77-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 641-77-0 Formula: C21H30O4 Molecular Weight: 346.46100

Description

A metabolite of Fluticasone propionate.

Basic Info

Chemical Name	11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
Synonyms	21 DEOXYCORTISOL 21-DESOXYCORTISOL; 4-pregnene-11-B-17-A-diol-3-20-dione; 21-DESOXYCORTISOL; 21-deoxycortisol; 4-Pregnen-11,17a-diol-3,20-dione-d8; 21-Dehydrohydrocortisone; 21-Deoxyhydrocortisone;
CAS No.	641-77-0
Molecular Formula	C21H30O4
Molecular Weight	346.46100
PSA	74.60000
LogP	2.80920

Properties

Density	1.21g/cm3
Boiling Point	523.9ºC at 760 mmHg
Flash Point	284.7ºC
Refractive Index	1.576

Synthesis Route

11β,17α-dihydroxy-17-pregn-4-en-20-yn-3-one→11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
11β,17α-dihydroxy-21-iodopregn-4-ene-3,20-dione→11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
11β,17α-dihydroxy-21-iodopregn-4-ene-3,20-dione→11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE+tixocortol

Precursor

4β-chloro-17-hydroxy-5β-pregnane-3,11,20-trione
11β,17α-dihydroxy-17-pregn-4-en-20-yn-3-one
11β,17α-dihydroxy-21-iodopregn-4-ene-3,20-dione
4β-bromo-11β,17-dihydroxy-5β-pregnane-3,20-dione

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