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10β-Hydroxy Norethindrone

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Origin: China

Cas No: 1236-00-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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CAS No.: 1236-00-6 Formula: C20H26O3 Molecular Weight: 314.41900

Description

10β-Hydroxynorethindrone is the 6β-hydroxy analogue and a by-product of Norethindrone synthesis. 10β-Hydroxynorethindrone is also a metabolite of the progestagen hormone, Lynestrenol.

Basic Info

Chemical Name	10β-Hydroxy Norethindrone
Synonyms	(8S,9S,10S,13S,14S,17R)-17-ethynyl-10,17-dihydroxy-13-methyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;
CAS No.	1236-00-6
Molecular Formula	C20H26O3
Molecular Weight	314.41900
PSA	57.53000
LogP	2.60740

Properties

Density	1.23g/cm3
Boiling Point	486.9ºC at 760mmHg
Flash Point	262.4ºC
Refractive Index	1.598
Vapor Pressure	1.59E-11mmHg at 25°C

Synthesis Route

Lynestrenol→19-nor-17α-pregn-4-en-20-yn-3β,6β,17β-triol+(6R,8R,9S,10R,13S,14S,17R)-17-ethynyl-6,17-dihydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
(8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one→10β-Hydroxy Norethindrone

Precursor

(8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
Lynestrenol

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